Table 4.
Correlation between interstitial inflammation, each component of activity index and chronicity index and Bcl-2 positivity in the patients with lupus nephritis
| Pathological characteristics | Coefficient | p-value |
|---|---|---|
| Activity index | 0.487 | <0.001 |
| Endocapillary hypercellularity | 0.350 | 0.001 |
| Neutrophils/Karyorrhexis | 0.178 | 0.090 |
| Fibrinoid necrosis | –0.042 | 0.693 |
| Hyaline deposits | –0.112 | 0.288 |
| Cellular/fibrocellular crescents | 0.268 | 0.010 |
| Interstitial inflammation | ||
| Chronicity index | 0.653 | <0.001 |
| Glomerulosclerosis | 0.476 | <0.001 |
| Fibrous crescents | 0.049 | 0.643 |
| Tubular atrophy | 0.622 | <0.001 |
| Interstitial fibrosis | 0.642 | <0.001 |
| Total Bcl-2 | 0.538 | 0.004 |
| Bcl-2 positive in CD4 | 0.533 | 0.005 |
| Bcl-2 positive in CD20 | 0.471 | 0.015 |
Correlations between interstitial inflammation, each components of AI and CI and Bcl-2 positivity. Correlations are expressed by using Spearman correlation coefficients. Bcl-2: B-cell lymphoma-2 protein, AI: activity index, CI: chronicity index.