Table 3.

Application in modification of natural products for antimicrobial activity.

Parent compound	Derivative	Target	Pharmacological activity(EC50)	Reference
Magnolol	48	B. cinerea	2.86 μg·mL−1	69
Magnolol	49	F. graminearum	4.39 μg·mL−1	69
		R. solani	1.40 μg·mL−1
Magnolol	50	S. sclerotiorum	5.04 μg·mL−1	69
Magnolol	51	S. sclerotiorum	4.64 μg·mL−1	69
Ampicillin	52	S. aureus	1.95 μg·mL−1	70
		B. subtilis	1.95 μg·mL−1
Ampicillin	53	S. aureus	3.91 μg·mL−1	70
		B. subtilis	3.91 μg·mL−1
Ampicillin	54	S. aureus	7.81 μg·mL−1	70
		B. subtilis	7.81 μg·mL−1
		E. coli	31.25 μg·mL−1
		P. aeruginosa	31.25 μg·mL−1
Luteolin	55	Staphylococcus aureus	2 mg·L−1	71
		Listeria monocytogenes	2 mg·L−1
		Escherichia coli	4 mg·L−1
		S. gallinarum	0.125 mg·L−1
Kaempferol	56	Staphylococcus aureus	1 mg·L−1	71
		Listeria monocytogenes	0.5 mg·L−1
		Escherichia coli	2 mg·L−1
		S. gallinarum	0.05 mg·L−1
Lawsone	57	C. albicans ATCC 10231	20 μg·mL−1	72
		C. glabrata ATCC 2001	170 μg·mL−1
Lawsone	58	C. albicans ATCC 10231	85 μg·mL−1	72
		C. glabrata ATCC 2001	330 μg·mL−1
Eugenol	59	albicans ATCC10231	600.8 μg·mL−1	73
		C. krusei ATCC 6258	600.8 μg·mL−1
	61	Botrytis cinerea	2.1 nM	74
		Colletotrichum capsici	19 nM
		Rhizoctonia solani	5.8 nM
Obovatol	63	B. cinerea	28.68 μg·mL−1	83
	64	A. solani	63.19 μg·mL−1	83
		F. solani	59.13 μg·mL−1
		B. cinerea	16.9 μg·mL−1
Berberine	65	B. yeast	16 μg·mL−1
		A. flavus	32 μg·mL−1