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. 2023 Jul 17;131(7):077007. doi: 10.1289/EHP12603

Figure 1.

Figures 1A and 1D are horizontal clustered bar graphs, plotting year of serum collection, ranging from 1999 to 2000, 2003 to 2004, 2005 to 2006, 2007 to 2008, 2009 to 2010 (y-axis) across perfluorooctanesulfonic acid geometric mean (nanogram per milliliter), ranging from 0 to 50 in increments of 10; perfluorooctanoic acid geometric mean (nanogram per milliliter), ranging from 0 to 8 in unit increments; perfluorohexanesulfonic acid geometric mean (nanogram per milliliter), ranging from 0 to 6 in unit increments; and 2-(N-methyl-perfluorooctane sulfonamido) acetate acetic acid geometric mean (nanogram per milliliter), ranging from 0 to 3 in unit increments (x-axis) for samples from the Department of Defense Serum Repository (study controls only) and the National Health and Nutrition Examination Survey.

Comparisons of geometric mean serum concentrations (ng/mL) of selected PFAS in DoDSR Air Force study controls (first/only sample) vs. male participants age 18–39 y in the National Health and Nutrition Examination Survey (NHANES) for samples collected in 1999–2000 (controls, n=77; NHANES, n=204), 2003–2004 (controls, n=50; NHANES, n=375), 2005–2006 (controls, n=44; NHANES, n=352), 2007–2008 (controls, n=34; NHANES, n=347), and 2009–2010 (controls, n=25; NHANES, n=360). (A) PFOS; (B) PFOA; (C) PFHxS; (D) MeFOSAA. p-Values are from Wilcoxon rank sum tests of difference in PFAS concentration between populations for a given sample collection period. The estimated geometric means of all seven evaluated PFAS in study controls and NHANES data are provided in Supplementary Table 2. Note: DoDSR, Department of Defense Serum Repository; MeFOSAA, 2-(N-methyl-perfluorooctane sulfonamido) acetic acid; NHANES, National Health and Nutrition Examination Survey; PFHxS, perfluorohexanesulfonic acid; PFOA, perfluorooctanoic acid; PFOS, perfluorooctanesulfonic acid.