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. 2023 Jul 3;14:1219907. doi: 10.3389/fimmu.2023.1219907

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Copyright © 2023 Steele, Cheng, Willicut, Dell, Breckenridge, Culberson, Ghastine, Tardif and Herro

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LIGHT Activity on Structural and Immune Cells. LIGHT (TNFSF14) can act directly on structural cells (epithelial cells, smooth muscle cells, fibroblasts) and immune cells (granulocytes, macrophages) to drive pro-fibrotic and anti-fibrotic effects. Figure was created with BioRender.com.