Figure 2.
NfL levels in AMN, CALD, and CBALD patients. (A) cNfL levels in AMN (n = 14), CALD (n = 22), and CBALD patients (n = 5) who did not undergo HSCT. The median cNfL levels and the interquartile ranges were indicated by a gray box. The difference in means between groups was statistically significant (p = 2.4 × 10−5, Kruskal–Wallis multiple comparison tests). The p‐values were obtained with the nonparametric Steel–Dwass test. n.s., not statistically significant. (B) Receiver operating characteristic (ROC) curve for the capability of cNfL level to discriminate CALD from AMN. Area under the curve (AUC) = 0.964 (0.91–1 CI 95%).