Table 1.
Differences between with favorable prognosis group and the unfavorable prognosis group in the development cohort (univariate analysis).
Variable | Total (n = 687) | Unfavorable prognosis (n = 264) | Favorable prognosis (n = 423) | p‐value |
---|---|---|---|---|
Gender (male) | 265 (38.57%) | 103 (39.02%) | 162 (38.30%) | 0.915 |
Age | 58 (50–65) | 60 (52–67) | 56 (48–63) | <0.001 |
Smoking | 44 (6.40%) | 10 (3.79%) | 34 (8.04%) | 0.031 |
Alcohol abuse | 34 (4.95%) | 7 (2.65%) | 27 (6.38%) | 0.044 |
Hypertension | 270 (39.30%) | 117 (44.32%) | 153 (36.17%) | 0.041 |
Diabetes | 49 (7.13%) | 25 (9.47%) | 24 (5.67%) | 0.084 |
Dyslipidemia (Yes vs No) | 99 (14.41%) | 32 (12.1%) | 67 (15.8%) | 0.216 |
History of stroke (Yes vs No) | 3 (0.44%) | 3 (1.14%) | 0 (0%) | 0.056 |
Level on GCS score | <0.001 | |||
Mild (13–15 score) | 455 (66.23%) | 98 (37.12%) | 357 (84.40%) | |
Moderate (9–12 score) | 94 (13.68%) | 52 (19.70%) | 42 (9.93%) | |
Severe (3–8 score) | 138 (20.09%) | 114 (43.18%) | 24 (5.67%) | |
Hunt‐Hess grade | <0.001 | |||
I | 137 (19.94%) | 27 (10.23%) | 110 (26.00%) | |
II | 131 (19.07%) | 21 (7.95%) | 110 (26.00%) | |
III | 266 (38.72%) | 92 (34.85%) | 174 (41.13%) | |
IV | 130 (18.92%) | 102 (38.64%) | 28 (6.62%) | |
V | 23 (3.35%) | 22 (8.33%) | 1 (0.24%) | |
mFS grade | <0.001 | |||
0 | 3 (0.44%) | 3 (1.14%) | 0 (0%) | |
I | 107 (15.57%) | 16 (6.06%) | 91 (21.51%) | |
II | 347 (50.51%) | 111 (42.05%) | 236 (55.79%) | |
III | 138 (20.09%) | 90 (34.09%) | 48 (11.35%) | |
IV | 92 (13.39%) | 44 (16.67%) | 48 (11.35%) | |
NIHSS score | 2 (0–13) | 17.5 (3–36) | 1 (0–4) | <0.001 |
Cerebral parenchymal hematoma (Yes vs No) | 112 (16.30%) | 70 (26.52%) | 42 (9.93%) | <0.001 |
Hydrocephalus (Yes vs No) | 50 (7.29%) | 35 (13.26%) | 15 (3.55%) | <0.001 |
Location of aneurysm | 0.887 | |||
Internal carotid artery | 119 (17.32%) | 46 (17.42%) | 73 (17.26%) | |
Middle cerebral artery | 185 (26.93%) | 77 (29.17%) | 108 (25.53%) | |
Former traffic artery | 239 (34.79%) | 89 (33.71%) | 150 (35.46%) | |
Rear traffic artery | 122 (17.76%) | 45 (17.05%) | 77 (18.20%) | |
Vertebral artery | 14 (2.04%) | 5 (1.89%) | 9 (2.13%) | |
Basilar artery | 8 (1.16%) | 2 (0.76%) | 6 (1.42%) | |
Multiple (Yes vs No) | 96 (13.97%) | 39 (14.77%) | 57 (13.48%) | 0.716 |
Stent implantation (Yes vs No) | 92 (13.39%) | 33 (9.07%) | 59 (13.95%) | 0.669 |
Blood glucose | 8.40 (7.00–10.79) | 9.75 (8.07–12.38) | 7.80 (6.66–9.40) | <0.001 |
MAP, mmHg | 136 (120–153) | 133.33 (118.50–149.83) | 139.83 (122.67–156.33) | 0.002 |
Serum calcium level | 2.27 (2.18–2.36) | 2.27 (2.18–2.36) | 2.27 (2.17–2.36) | 0.947 |
Leukocyte count | 13.84 (10.67–17.01) | 15.70 (12.61–20.08) | 12.41 (9.64–15.62) | <0.001 |
Neutrophil count | 11.61 (8.25–14.64) | 13.32 (10.54–17.32) | 10.09 (7.62–13.36) | <0.001 |
Lymphocyte count | 1.36 (0.91–2.00) | 1.38 (0.90–2.32) | 1.35 (0.92–1.88) | 0.148 |
Monocyte count | 0.56 (0.38–0.78) | 0.66 (0.44–0.94) | 0.51 (0.35–0.70) | <0.001 |
Platelet count | 236 (197–275) | 242.00 (204.75–275.25) | 231.00 (194.00–274.00) | 0.046 |
NLR | 8.81 (4.98–14.03) | 10.74 (5.75–15.38) | 8.16 (4.65–13.04) | <0.001 |
MLR | 0.38 (0.26–0.58) | 0.43 (0.28–0.66) | 0.37 (0.25–0.53) | <0.001 |
PLR | 169.52 (115.19–254.10) | 167.76 (104.95–261.55) | 169.77 (122.63–247.56) | 0.594 |
NWR | 0.85 (0.78–0.90) | 0.86 (0.80–0.90) | 0.85 (0.76–0.89) | 0.012 |
MNM | 5.70 (3.25–10.21) | 8.19 (4.99–15.02) | 4.67 (2.85–8.12) | <0.001 |
GCS, Glasgow Coma Scale; MAP, mean arterial pressure; mFS grade, modified Fisher grade; MLR, monocyte to lymphocyte ratio; MNM, multiplication to neutrophil and monocyte counts; NIHSS, National Institutes of Health Stroke Scale; NLR, neutrophil to lymphocyte ratio; NWR, neutrophil to leukocyte ratio; PLR, platelet to lymphocyte ratio.