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. 2023 Jul 3;10:1219830. doi: 10.3389/fmed.2023.1219830

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Copyright © 2023 Chu, Cong, Zhao, Zhang, Lou, Gao and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Classification of hub genes (A–C). The difference in HTRA1 (p = 2.222e-08), P2RY6 (p = 1.335e-06), and RCAN1 (p = 0.001) levels could be observed in OA compared with control groups. HTRA1, HtrA serine peptidase 1; P2RY6, pyrimidinergic receptor P2Y6; RCAN1, regulator of calcineurin 1.