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. 2023 May 16;41(21):3712–3723. doi: 10.1200/JCO.22.02459

FIG 2.

FIG 2.

Safety profiles and activity of ICIs among PWH. (A) irAEs by type; cumulative incidence of irAEs among (B) CD4+ T-cell counts and (C) CD4:CD8 ratio subgroups; and (D) ORR across top 10 cancer types. HCC, hepatocellular carcinoma; HL, Hodgkin lymphoma; HNSCC, head and neck squamous cell carcinoma; ICI, immune checkpoint inhibitor; irAEs, immune-related adverse events; KS, Kaposi sarcoma; NHL, non-Hodgkin lymphoma; NSCLC, non–small-cell lung cancer; ORR, objective response rate; PWH, people living with HIV; SCLC, small-cell lung cancer.