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. 2022 Nov 3;51(4):921–934. doi: 10.1007/s15010-022-01948-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Risk factors for eradication failure applied from multivariable logistic regression among treatment naïve patients (group A) with known antibiotic susceptibility of clarithromycin (CLA) & metronidazole (MET), who received tailored triple therapy (TTT) and completed follow-up, N = 503. Abbreviations: TTT tailored triple therapy, ER eradication rate, OR odd ratio, PPI proton pump inhibitor, AMO amoxicillin, CLA clarithromycin, MET metronidazole, MET-S/CLA-S strains susceptible to both metronidazole and clarithromycin, MET-S/CLA-R strains susceptible to metronidazole but resistant to clarithromycin, MET-R/CLA-S strains resistant to metronidazole but susceptible to clarithromycin, MET-R/CLA-R strains resistant to both metronidazole and clarithromycin. Odds ratios (OR) with 95% confidence intervals (95% CI) obtained from the final multivariable logistic regression are given. P values were obtained from the Wald Chi-Square Test for the significance of the odds ratio (OR)