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. 2023 Jul 17;14(7):442. doi: 10.1038/s41419-023-05947-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Cell clusters of the PT of db/m mice and db/db mice. UMAP representation of the PT of db/m mice and db/db mice. B The specific markers of cell cluster of PT subtypes. C The percentage of each PT subtypes. D Weighted analysis of the expression of proliferative markers (TOP2A, MKi67) in four PT subtypes. E The kidneys of db/m mice and db/db mice were collected and staining by CODEX multiplexed tissue staining. PT (AQP1, green), proliferative PT (MKi67, red), DAPI (blue). Scale bars, 120 μm. ▲ (proliferative PT).