Table 1.
Baseline patient characteristics.
| Variable | All | Survivors | Non-survivors | P value |
|---|---|---|---|---|
| (n = 816) | (n = 593, 72.7%) | (n = 223, 27.3%) | ||
| Demographics | ||||
| Age (yrs), median (IQR) | 77 (67–83) | 76 (66–83) | 78 (68–85) | 0.050 |
| Males, n (%) | 588 (72.1%) | 427 (72.0%) | 161 (72.2%) | 1.000 |
| BMI (kg/m2), mean (SD) | 20.7 (4.5) | 20.8 (4.6) | 20.3 (4.1) | 0.255 |
| Smoking | 0.002 | |||
| Ex-smoker, n (%) | 233 (28.6%) | 173 (29.2%) | 60 (26.9%) | |
| Current smoker, n (%) | 43 (5.3%) | 21 (3.5%) | 22 (9.9%) | |
| Pack years in ever-smokers, mean (SD) | 9.9 (19.0) | 9.1 (18.0) | 11.8 (21.1) | 0.083 |
| Underlying comorbidities | ||||
| Hypertension, n (%) | 450 (55.1%) | 334 (56.3%) | 116 (52.0%) | 0.306 |
| Diabetes, n (%) | 319 (39.1%) | 240 (40.5%) | 79 (35.4%) | 0.216 |
| COPD, n (%) | 62 (7.6%) | 42 (7.1%) | 20 (9.0%) | 0.449 |
| Asthma, n (%) | 24 (2.9%) | 16 (2.7%) | 8 (3.6%) | 0.662 |
| Interstitial lung disease, n (%) | 31 (3.8%) | 14 (2.4%) | 17 (7.6%) | < 0.001 |
| Nontuberculous mycobacteria, n (%) | 8 (1.0%) | 4 (0.7%) | 4 (1.8%) | 0.295 |
| Tuberculosis, n (%) | 119 (14.6%) | 82 (13.8%) | 37 (16.6%) | 0.376 |
| Lung cancer, n (%) | 11 (1.3%) | 4 (0.7%) | 7 (3.1%) | 0.017 |
| Chronic kidney disease, n (%) | 121 (14.8%) | 77 (13.0%) | 44 (19.7%) | 0.021 |
| Chronic liver disease, n (%) | 48 (5.9%) | 34 (5.7%) | 14 (6.3%) | 0.898 |
| Cardiovascular disease, n (%) | 14 (1.7%) | 5 (0.8%) | 9 (4.0%) | 0.005 |
| Congestive heart failure, n (%) | 32 (3.9%) | 14 (2.4%) | 18 (8.1%) | < 0.001 |
| Cerebrovascular accident, n (%) | 11 (1.3%) | 5 (0.8%) | 6 (2.7%) | 0.089 |
| Dementia, n (%) | 63 (7.7%) | 44 (7.4%) | 19 (8.5%) | 0.706 |
| HIV, n (%) | 5 (0.6%) | 3 (0.5%) | 2 (0.9%) | 0.893 |
| Metastatic cancer, n (%) | 11 (1.3%) | 3 (0.5%) | 8 (3.6%) | 0.002 |
| Hematologic malignancy, n (%) | 2 (0.2%) | 1 (0.2%) | 1 (0.4%) | 1.000 |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; HIV, human immunodeficiency virus.