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. 2023 Jul 17;3:98. doi: 10.1038/s43856-023-00329-2

Fig. 3. Global visualization of gene expression signature similarity for LINCS drugs.

Fig. 3

UMAP of 718,055 L1000 perturbations, colored by a FDA D and X category; b known placental crossing; c top MOAs across clusters. Clusters computed using HDBSCAN with a minimum cluster size of 40, top 25 clusters for each category, and top five MOAs of those clusters are included.