Table 3.

Solvent consumption for one and two consecutive CCC runs in co-current mode (ccCCC). The respective amount of solvent was calculated with 52 min in co-current (cc) flow per run, with an S_f value of 88%, a coil volume of 236 mL and F_m = 2 mL/min and F_s = 4 mL/min in tail-to-head mode

ccCCC runs	Lower phase		Upper phase
	Coil loading [mL]	cc flow [mL]	Equilibration [mL]	cc flow [mL]
1x	236	208	29	104
2x	236	416	29	208
∑1x	444 mL		133 mL
∑2x	652 mL		237 mL