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. 2023 Jul 4;15:1155630. doi: 10.3389/fnagi.2023.1155630

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Copyright © 2023 Ephrame, Cork, Marshall, Johnston, Shawa, Alghusen, Qiang, Denson, Carman, Fedosyuk, Swerdlow and Slawson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Western blot analysis of samples harvested after serum reactivation time course in panels (A,B) SH-SY5Y neuroblastoma cells and (D,E) HeLa cervical cancer cells subjected to long term OGA inhibition with TMG. (C,F) Densitometry plot of ERK 1/2 phosphorylation normalized to total ERK 1 in SH-SY5Y cells (n = 4) and HeLa (n = 5), where n = total number of experimental trials. Dots represent the number of experimental trials (n). Statistical significance was measured using paired-t-test analysis and p-value is indicated on the plots. *Is added for p-values that are significant (p < 0.05).