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. 2023 Jul 4;14:1199465. doi: 10.3389/fimmu.2023.1199465

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Copyright © 2023 Shen, Huang, Li, Chen, Yao, Hu, Zhou, Huang and Ni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analyses of biological processes and pathways related to the LMRG-based signature. (A) Heatmap of the expression levels of all 1034 LMRGs showing distinct expression patterns between the high- and low-risk groups from the TCGA cohort. (B) Correlations between the two clusters and the two risk groups. The majority of patients in Cluster 2 were categorized into the low-risk group. (C) KEGG pathway analysis of the DEGs between the two risk groups, revealing differentially activated pathways. (D, E) Representative KEGG pathways and GO biological processes enriched in the high- and low-risk patients, as determined by GSEA.