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. 2023 Jul 18;13(31):21521–21536. doi: 10.1039/d3ra01581e

Effect of gemcitabine loaded different magnetic microspheres on hemostatic time and weight of whole blood clot in rat liver laceration and rat tail amputation test.

Gemcitabine loaded formulation Haemostasis time (s) Whole blood clot weight (mg) Rat liver laceration (weight of blood g) Rat tail amputation (weight of blood g)
Control 232 ± 6.08 82.4 ± 5.08 3.33 ± 0.03 1.33 ± 0.03
MHMG3 147 ± 5.93 144.7 ± 4.99 1.35 ± 0.03 1.02 ± 0.03
MCMG3 216 ± 6.08 216.2 ± 5.04 1.26 ± 0.03 1.00 ± 0.03
MHCMG7 89 ± 7.13 194.6 ± 5.99 0.03 ± 0.001 0.50 ± 0.003