Table 3.

MDR Interaction Analysis between SNPs and Tobacco (Gene-Environment Interaction)

MDR model	Balanced accuracy CV training	Balanced accuracy CV testing	CV consistency	Permutation test ‘p’ value
Tobacco	0.682	0.682	10/10	<0.001
Tobacco - CYP1A1*2C, rs4646903	0.6835	0.6694	7/10	<0.001
Tobacco,- CYP1A1*2C, rs4646903, -p53 Intron 3 rs17878362 - Intron 6 rs1625895	0.7047	0.6333	7/10	0.01

CVC, Cross Validation Consistency; p-values as calculated after 1000 permutations