Table 3.
miRNAs encapsulated in VSMC-EVs regulate in the process of AS.
| miRNA | EVs origin | Stimulation | Expression | Function | References |
|---|---|---|---|---|---|
| miR-143-3p | HCASMC | Hypercholesterolemia | Down | Cardiovascular biomarker | (140) |
| miR-222-3p | HCASMC | Hypercholesterolemia | Down | Cardiovascular biomarker | (140) |
| miR-155-5p | HASMC | KLF5 | Up | Promoted as | (150) |
| miR-24-3p | HCASMC | Atherogenic lipoprotein | Down | Further researched required | (159) |
| miR-29b-3p | HCASMC | Atherogenic lipoprotein | Down | Further researched required | (159) |
| miR-130a-3p | HCASMC | Atherogenic lipoprotein | Down | Further researched required | (159) |
| miR143-3p | HCASMC | Atherogenic lipoprotein | Down | Further researched required | (159) |
| miR-222-3p | HCASMC | Atherogenic lipoprotein | Down | Further researched required | (159) |
EVs, extracellular vesicles; HCASMC, human coronary artery smooth muscle cell; HASMC, human artery smooth muscle cell; KLF5, Krüppel-like factor 5; AS, atherosclerosis.