Table 5.
lncRNAs encapsulated in EVs involved in the process of AS.
| lncRNA | EVs origin | Stimulation | Expression | Function | References |
|---|---|---|---|---|---|
| FENDRR | MSC | ox-LDL | Up | Inhibited as | (186) |
| LOC100129516 | MSC | si-LOC100129516 | Down | Promoted as | (187) |
| GAS5 | THP-1 | ox-LDL | Up | Promoted ec apoptosis | (188) |
| LIPCAR | THP-1 | ox-LDL | Up | Promoted as | (189) |
| MALAT1 | HUVEC | ox-LDL | Up | Promoted m2 macrophage polarization | (191) |
| MALAT1 | HUVEC | ox-LDL | Up | Promoted as | (192) |
| ZEB1-AS1 | HUVEC | ox-LDL | Up | Promoted as | (193) |
| LINC01005 | HUVEC | ox-LDL | Up | Promoted as | (194) |
| CLDN10-AS1 | HUVEC | ox-LDL | Up | Promoted ec injury | (195) |
EVs, extracellular vesicles; MSC, mesenchymal stem cell; ox-LDL, oxidized low-density lipoprotein; AS, atherosclerosis; HUVEC, human umbilical vein endothelial cell; EC, endothelial cell.