Table 6.
circRNAs encapsulated in EVs involved in the process of AS.
| circRNA | EVs origin | Stimulation | Expression | Function | References |
|---|---|---|---|---|---|
| CircNPHP4 | Monocyte | Coronary heart atherosclerotic disease | Up | Biomarker for as | (225) |
| hsa_circ_0001445 | HCASMC | Atherogenic lipoprotein | Down | Biomarker for cad | (226) |
| hsa_circ_0005699 | Serum | Coronary heart disease | Down | Biomarker for as | (227) |
| circ_0006896 | Serum | Unstable plaque as | Up | Linked to plaque destabilization | (228) |
| circ_0043837 | Serum | Large artery atherosclerotic stroke | Down | Biomaker for stroke in as | (229) |
| circ_ 0001801 | Serum | Large artery atherosclerotic stroke | Down | Biomaker for stroke in as | (229) |
| hsa_circ_0086296 | HUVEC and serum | ox-LDL or AS | Up | Promoted as | (230) |
EVs, extracellular vesicles; HCASMC, human coronary artery smooth muscle cell; AS, atherosclerosis; CAD, coronary artery disease; HUVEC, human umbilical vein endothelial cell; ox-LDL, oxidized low-density lipoprotein.