Table 2. In Vitro Inhibitory Activity of SW480 and HCT116 Colon Cancer Cells by Compounds 5–10 and 5-FU as the Reference Compound^a.

	EC50 (μM)b
compd	SW480	HCT116
5	28	50
6	27	45
7	>50	>50
8	45	47
9c	34	24
10	37	27
5-FUd,e	217	8
9f,g + 5-FU	63	8

^aExperiments were performed in duplicate or triplicate.

^bSD: Standard deviations went from ± 5% to ± 10% of the indicated EC₅₀ values.

^cInhibition of SW620 cells: 9, EC₅₀ = 37 μM.

^d5-FU, 5-fluorouracil.

^eInhibition of SW620 cells: 5-FU, EC₅₀ = 103 μM.

^fInhibition of SW620 cells: 9^g + 5-FU, EC₅₀ = 46 μM.

^g9 was at a constant concentration of 0.25 μM.