Table 3. Summary of Observed Pharmacokinetic Parametersa.

Abbreviations: MAMP (%), amount of methamphetamine excreted unchanged in the urine; AMP (%), amount of amphetamine excreted in the urine; AUC0-24, area under the concentration–time curve spanning 0 to 24 h; AUC0-∞, area under the concentration–time curve extrapolated from time 0 to an infinite time; Cmax, peak concentration; CL, clearance; Vd, volume of distribution; and t1/2, half-life. b = Administered as oral 2.5 mg dose followed 1.5 h later by intravenous 2.5 mg infusion over 30 min.