Skip to main content
. 2023 Jul 3;6(7):943–969. doi: 10.1021/acsptsci.3c00047

Table 6. Notable Patents Focused on the Development of mRNA Vaccines for Infectious Diseases.

Patent number Organization Patent title
WO2021213924 BioNTech, Germany Coronavirus RNA vaccine encoding SARS-CoV-2 spike protein for preventing COVID-19
WO2020190750 Moderna, U.S. Dept. of Health and Human Services, USA Preparation of HIV Env- and lentivirus Gag protein-encoding mRNA VLP vaccine to induce broad-spectrum neutralizing antibodies for treating HIV infection
WO2018151816 Moderna, USA Immunogenic compositions for Zika virus including cationic lipid nanoparticles encapsulating mRNA having an open reading frame encoding a viral, bacterial or parasitic antigen, a pan HLA DR-binding epitope (PADRE) and a 5′ terminal cap modified to increase mRNA translation efficiency
WO2021155243 Moderna, USA Respiratory virus vaccine compositions
WO2013055905 Novartis, Switzerland Recombinant self-replicating polycistronic RNA molecules expressing multiple herpes virus proteins and their use in vaccines for inducing neutralizing antibodies
WO2021159040 Moderna, USA Engineering SARS CoV-2 mRNA vaccines expressing key neutralizing domains of spike protein, individually or in combination, for inducing protective immunity and immunotherapy
WO2021251453 Daiichi Sankyo, University of Tokyo, Japan Nucleic acid lipid particle vaccine encapsulated with severe acute respiratory syndrome coronavirus 2 messenger ribonucleic acid
WO2021159130 Moderna, USA; U.S. Dept. of Health and Human Services, USA Preparation of SARS CoV-2 mRNA vaccines encoding full-length spike protein variant, stabilized into a prefusion conformation, encapsulated in a lipid nanoparticle formulation
WO2021255270 Ziphius Vaccines, Belgium; Universiteit Gent, Belgium Self-amplifying COVID-19 RNA vaccine encoding SARS-CoV-2 Spike and Nucleocapsid protein antigen and alphavirus Nonstructural protein
WO2017070613 Moderna, USA Human cytomegalovirus RNA vaccines
WO2021204179 Suzhou Abogen Biosciences, China Nucleic acid vaccines for coronavirus
WO2021226436 Translate Bio, USA; Sanofi, France Optimized nucleotide sequences encoding SARS-COV-2 antigens
WO2017070623 Moderna, USA Herpes simplex virus RNA vaccine
WO2021160346 Institut Pasteur, France Nucleic acid vaccine against severe acute respiratory syndrome coronavirus SARS-CoV-2
WO2022171182 Stemirna Therapeutics, China Vaccine reagent for treating or preventing coronavirus mutant strain
CA3132188 Providence Therapeutics Holdings, Canada Compositions and methods for the prevention and/or treatment of COVID-19
WO2021183563 Arcturus Therapeutics, USA Coronavirus vaccine compositions and methods
WO2022150717 Moderna, USA Seasonal RNA influenza virus vaccines
WO2022129918 Imperial College, UK Innovations Ltd, U.K. Engineering a thermally stabilized self-amplifying RNA vaccine based on Venezuelan Equine Encephalitis virus backbone encoding SARS-CoV-2 spike glycoprotein encapsulated in lipid nanoparticle formulation for preventing and/or treatment of COVID-19
WO2022178196 Sanofi Pasteur, USA Meningococcal B recombinant vaccine
WO2022137133 CureVac, Germany; GlaxoSmithKline Biologicals SA, U.K. RNA vaccine against SARS-CoV-2 variants
WO2022116528 Suzhou CureMed Biomedical Technology, China Circular RNA vaccine containing circular RNA and kit for detecting novel coronavirus neutralizing antibody
US20220325255 University of Texas, USA Compositions and methods for treating viral infections targeting TRIM7