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. 2023 Jul 3;6(7):943–969. doi: 10.1021/acsptsci.3c00047

Table 7. Notable Patents Focused on the Development of mRNA Vaccines for Cancer.

Patent number Organization Patent title
WO2021155149 Genentech, USA; BioNTech SE, Germany; F. Hoffmann-La Roche, Switzerland Methods of inducing neoepitope-specific T cells with a PD-1 axis binding antagonist and an RNA vaccine
WO2015024664 CureVac, Germany Composition comprising mRNA encoding a combination of tumor antigens as vaccine for treating prostate cancer
WO2012019168 ModernaTX, USA Use of modified mRNA encoding melanocyte stimulating hormone, insulin and granulocyte colony-stimulating factor in prevention or treatment of disorders
WO2020097291 ModernaTX, USA Cancer vaccines comprising mRNA(s) encoding peptide epitopes (neoepitopes) and formulated as lipid nanoparticles
WO2020141212 eTheRNA Immunotherapies NV, Belgium mRNA vaccine
WO2022008519 BioNTech SE, Germany; TRON – Translationale Onkologie Mainz, Germany Therapeutic RNA for HPV-positive cancer
WO2015024666 CureVac, Germany RNA vaccine for treating lung cancer
WO2012159643 BioNTech AG, Germany; TRON – Translationale Onkologie Mainz, Germany Individualized vaccines for cancer
WO2015014869 BioNTech AG, Germany; TRON – Translationale Onkologie Mainz, Germany Determination of expression pattern of a set of tumor antigens including Cxorf61, CAGE1, PRAME and others to select cancer therapy regimen
WO2022009052 Janssen Biotech, USA Prostate neoantigens and their uses
WO2022081764 RNAimmune, USA Pan-ras mRNA cancer vaccines
WO2014082729 BioNTech AG, Germany; Mainz Gemeinnuetzige GmbH, Germany Individualized vaccines for cancer
WO2016180467 BioNtech Cell & Gene Therapies, Germany; TRON – Translationale Onkologie Mainz, Germany Enhancing the effect of car-engineered T cells by means of nucleic acid vaccination