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. 2023 Jul 4;6(7):1052–1074. doi: 10.1021/acsptsci.3c00084

Table 4. Binding and Enzyme Inhibition Parameters of MARK4 with the Compoundsa.

compound €binding constant K, M–1 *IC50 (μM)
23a 6.3 × 107 0.82
23b 7.3 ×108 1.01
23c 1.9 × 106 1.49
16a 4.6 × 105 0.93
16b 6.7 × 105 0.912
16c 7.9 × 105 2
a

Values obtained from € Fluorescence and *Enzyme Inhibition Assay.