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. 2023 Aug;51(8):923–935. doi: 10.1124/dmd.122.001005

TABLE 1.

Typical alkaloidal content in kratom products and dried leaves

Alkaloid Range of Alkaloid Contenta (mg/g of Product)
mitragynine 0.5–270
speciogynine 3.18–33.4
mitraciliatine 0.647–4.75
speciociliatine 0.185–41.7
paynantheine 1.46–70.4
isopaynantheine 0.269–3.80
7-hydroxymitragynine 0.124–1.10
speciofoline 0.122–5.90
corynoxeine 0.290–1.22
corynoxine A 0.205–11.4
ajmalicine 0.192–0.648
rhynchophylline 0.239

aBased on two powdered plant products, a loose-leaf product, a liquid product, and an encapsulated powder (Manwill et al., 2022).