Table 2.
Characteristics of ICU patients
| Variables | DNR (n = 45) |
Withholding (n = 38) |
Withdrawal (n = 17) |
P |
|---|---|---|---|---|
| Reasons for ICU admission, n (%) | 0.503 | |||
| Respiratory failure | 22 (48.9) | 24 (63.2) | 11 (64.7) | |
| Septic shock | 18 (40.0) | 13 (34.2) | 5 (29.4) | |
| Others | 5 (11.1) | 1 (2.6) | 1 (5.9) | |
| SOFA score | ||||
| Within 24 h | 8.9 ± 4.1 | 8.5 ± 3.6 | 9.3 ± 3.7 | 0.770 |
| At 48 h | 10.9 ± 4.4 | 9.8 ± 4.8 | 9.8 ± 3.9 | 0.521 |
| Therapy within 24 h, n (%) | ||||
| Vasopressors | 36 (80.0) | 24 (63.2) | 11 (64.7) | 0.194 |
| Inotropes | 2 (4.4) | 0 (0.0) | 2 (11.8) | 0.093 |
| HFNC | 17 (37.8) | 15 (39.5) | 5 (29.4) | 0.767 |
| MV | 29 (64.4) | 21 (55.3) | 10 (58.8) | 0.692 |
| Therapy during ICU stay, n (%) | ||||
| HFNC | 19 (42.2) | 20 (52.6) | 6 (35.3) | 0.431 |
| MV | 35 (77.8) | 26 (68.4) | 13 (76.5) | 0.655 |
| RRT | 21 (46.7) | 6 (15.8) | 5 (29.4) | 0.011 |
| ECMO | 1 (2.2) | 0 (0.0) | 2 (11.8) | 0.074 |
| Events during ICU stay, n (%) | ||||
| Ventilator-associated pneumonia | 8 (17.8) | 4 (10.5) | 3 (17.6) | 0.698 |
| Catheter-related infection | 6 (13.3) | 1 (2.6) | 0 (0.0) | 0.098 |
| Urinary tract infection | 4 (8.9) | 3 (7.9) | 2 (11.8) | 0.810 |
| ARDS | 9 (20.0) | 13 (34.2) | 3 (17.6) | 0.294 |
| Arrhythmia | 14 (31.1) | 5 (13.2) | 2 (11.8) | 0.099 |
| Bleeding requiring intervention | 6 (13.3) | 2 (5.3) | 0 (0.0) | 0.225 |
| Cardiopulmonary resuscitation | 5 (11.1) | 3 (7.9) | 1 (5.9) | 0.902 |
| ICU duration | 8 (5–20) | 9.5 (5–17) | 15 (6–32) | 0.399 |
| MV duration | 5 (1–15) | 5 (0–12) | 4 (3–15) | 0.879 |
| ICU mortality | 40 (88.9) | 27 (71.1) | 11 (64.7) | 0.048 |
| 30-day mortality after ICU admission | 38 (84.4) | 32 (84.2) | 9 (52.9) | 0.026 |
| 60-day mortality after ICU admission | 40 (88.9) | 36 (94.7) | 15 (88.2) | 0.581 |
Values are presented as the mean ± SD, median (IQR), or number (%)
ICU Intensive care unit, DNR Do not resuscitate, SOFA Sequential Organ Dysfunction Assessment, HFNC High-flow nasal cannula, MV Mechanical ventilation, RRT Renal replacement therapy, ECMO Extracorporeal membrane oxygenation, ARDS Acute respiratory distress syndrome