Table 2.

Characteristics of 1278 participants grouped by ACS cases and controls

Variable*	Case (n = 639)	Control (n = 639)	P
Age, years	65.15 ± 7.22	65.00 ± 7.34	0.710
Lym	0.317 (0.270–0.373)	0.321 (0.271–0.372)	0.994
Mono	0.064 (0.050–0.079)	0.063 (0.048–0.080)	0.329
Neu	0.554 (0.501–0.612)	0.555 (0.502–0.607)	0.789
CD8T	0.084 (0.058–0.116)	0.084 (0.055–0.116)	0.835
CD4T	0.100 (0.069–0.133)	0.096 (0.068–0.127)	0.127
B	0.029 (0.017–0.044)	0.028 (0.016–0.041)	0.109
NK	0.092 (0.065–0.126)	0.100 (0.071–0.129)	0.026
Obesity, n (%)	92 (14.40)	58 (9.08)	4.13 × 10–3
Hypertension, n (%)	478 (74.80)	381 (59.62)	1.06 × 10–8
Hyperlipidemia, n (%)	326 (51.02)	239 (37.40)	1.27 × 10–6
Diabetes, n (%)	168 (26.29)	118 (18.47)	1.01 × 10–3
Smoking status, n (%)
Current smoking	137 (21.44)	115 (18.00)	0.074
Past smoking	85 (13.30)	67 (10.49)	0.075

*The proportions of leukocyte subtypes are those estimated from DNA methylation profiles. Lym lymphocyte proportion, Mono monocyte proportion, Neu neutrophil proportion, CD8T CD8⁺ T cell proportion, CD4T CD4⁺ T cell proportion, B B cell proportion, NK natural killer cell proportion