Table 2.
Summary of laboratory evaluation
| Twin A | Twin B | Normal range | ||
|---|---|---|---|---|
| CSF HSV (PCR) | Negative | Negative | – | |
| CMV (IgM) | 0.3 | Negative | < 0.85 | |
| CMV (IgG) | 208 | Negative | < 6 | |
| EBV VCA IgM | 1.89 | Negative | < 0.5 | |
| EBV VCA IgG | 3.65 | Negative | < 0.75 | |
| HIV AB | Negative | Negative | – | |
| C3 | 0.71 | 0.9 | 0.89–1.87 | |
| C4 | 0.27 | 0.35 | 0.165–0.38 | |
| Immunoglobulins | ||||
| IgG (g/L) | 7.6 | 9.2 | 6.58–18.37 | |
| IgM (g/L) | 0.49 | 0.9 | 0.4–2.5 | |
| IgA (g/L) | 0.52 | 1.1 | 0.8–3.5 | |
| IgE (IU/mL) | 33 | 29 | < 144 | |
| Isohemagglutinin, Anti A, IgM | 1/4 | 1/16 | ||
| Isohemagglutinin, Anti B, IgM | 1/8 | 1/32 | ||
| Blood flow cytometry analysis: lymphocytes subsets (%) | ||||
| CD3 | 44 | 72 | 35–78 | |
| CD4 | 5 | 4 | 22–62 | |
| CD8 | 36 | 64 | 12–36 | |
| CD19 | 14 | 15 | 3–14 | |
| CD20 | 14 | 16 | 3–15 | |
| CD16 | 1.36 | 4 | 3–17 | |
| CD56 | 25.5 | 11.5 | 3–17 | |
| CD4/CD8 | 0.13 | 0.06 | 1–3 | |
HSV herpes simplex virus, CMV cytomegalovirus, EBV Epstein–Barr virus, Ig immunoglobulin