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. 2023 Jul 18;21:479. doi: 10.1186/s12967-023-04280-7

Table 2.

Categories of BMI, WC, physical activity, and hs-CRP of the study population at baseline and after 31 days of active stage of VLCKD

Parameters Baseline
Mean ± SD or number (%)
n = 324
Day 31 of VLCKD
Mean ± SD or number (%)
n = 324
∆% *p-value
BMI categories
 Normal-weight 0, 0% 13, 4.0% + 4.0% χ2 = 11.30, p < 0.001
 Overweight 54, 16.7% 97, 29.9% + 13.2% χ2 = 15.23, p < 0.001
 Grade I obesity 103, 31.8% 105, 32.4% + 0.6% χ2 = 0.01, p = 0.933
 Grade II obesity 100, 30.8% 78, 24.1% − 6.8% χ2 = 3.42, p = 0.065
 Grade III obesity 67, 20.7% 31, 9.6 − 11.1% χ2 = 14.73, p < 0.001
WC categories
 < Cut-off 50, 15.4% 93, 28.7% + 13.3% χ2 = 15.83, p < 0.001
 > Cut-off 274, 84.6% 231, 71.3%
Physical activity
 Yes 102, 31.5% 102, 31.5% 0% χ2 = 0.01, p = 0.933
 No 222, 68.5% 222, 68.5%
ahs-CRP categories
 < 1.0 mg/L 52, 19.8% 108, 41.1% + 21.6% χ2 = 27.17, p < 0.001
 1.0–3.0 mg/L 96, 36.5% 116, 44.1% + 7.6% χ2 = 2.85, p = 0.091
 ≥ 3.0 mg/L 115, 43.7% 39, 14.8 − 28.9% χ2 = 51.65, p < 0.001

SD standard deviation, VLCKD very low-calorie ketogenic diet, BMI body mass index, WC waist circumference, hs-CRP high-sensitivity C-reactive protein

*A p value in bold type denotes a significant difference (p < 0.05)

ahs-CRP levels were evaluated in a subgroup of 263 women