Table 1.
List of the upregulated and downregulated hub genes in each group. The value of gene expression is showed by LogFC. A positive LogFC indicates an increase in gene expression in HAM/TSP patients compared to ATLL patients. The statistically significant value between the two mentioned groups is showed by adjusted P. Value
| Symbol | logFC | adj.P.Val | Symbol | logFC | adj.P.Val |
|---|---|---|---|---|---|
| ATM | 1.43 | 0.00021 | RAD1 | 1.71 | 0.00905 |
| CD80 | -1.51 | 0.00001 | GTF2F2 | -2.35 | 0.00301 |
| CXCR4 | -1.41 | 0.04006 | SELPLG | -2.65 | 0.00006 |
| PIK3R1 | -1.52 | 0.01943 | S100A4 | -2.11 | 0.00008 |
| CD2 | -1.68 | 0.00047 | TIAL1 | 1.46 | 0.01677 |
| CD48 | -2.91 | 0.00001 | ADCY7 | -1.45 | 0.00244 |
| SOCS1 | 1.41 | 0.01001 | AHNAK | -2.07 | 0.00039 |
| S100B | 1.74 | 0.00130 | APOB | 1.56 | 0.00749 |
| APP | 1.71 | 0.00126 | SERPIND1 | 1.47 | 0.00011 |
| CXCL9 | -1.57 | 0.00151 | EPHA4 | -1.60 | 0.00123 |
| SPN | 1.60 | 0.00300 | NEFL | -1.61 | 0.00876 |
| ITGA2 | -1.98 | 0.00484 | UNG | -1.40 | 0.00082 |
| SIRT3 | -1.59 | 0.00032 | CFLAR | -1.89 | 0.00013 |
| RAD54L | -1.47 | 0.00014 | TLK1 | -1.44 | 0.00124 |
| KLRB1 | -2.56 | 0.00001 | PARG | -1.49 | 0.00554 |
| IGF1R | 1.50 | 0.00013 | CDKN2D | -1.65 | 0.00288 |
| CDC7 | -2.19 | 0.00008 | ATP5J | -1.88 | 0.00008 |
| XPA | -1.42 | 0.00013 | CALM1 | -1.42 | 0.00406 |
| SDHA | -1.78 | 0.00124 | IWS1 | -1.70 | 0.00021 |
| CCNT2 | -1.57 | 0.00013 | CDK8 | -1.39 | 0.00008 |
| LILRB1 | 0.35 | 0.26656 | TRAF3IP3 | -1.47 | 0.00710 |
| CD83 | -1.80 | 0.00001 | LAIR1 | -1.71 | 0.00171 |
| PRKAR2B | -1.60 | 0.00018 | TNFSF11 | -1.71 | 0.00171 |
| SERPING1 | -1.66 | 0.00008 | LRRFIP1 | -1.71 | 0.00059 |
| PRMT1 | 1.88 | 0.06741 | LGALS3BP | 1.54 | 0.01576 |
| WEE1 | -1.64 | 0.00022 |