TABLE 2.

Smp145 epitope affinity on different MHC-II haplotypes in the population^a

DRB1 allele (human)	Distribution of DRB1 alleles in the population (ethnic group)	Reference	Peptide	Core	Affinityb
0101	Caucasians, Native Americans, Asian/Islanders, Hispanics, and in African Americans	25	IVFINFHNNGQDHLLKAVTNSLASI	LLKAVTNSL	WB
0401	Eskimos and Caucasians	26	IVFINFHNNGQDHLLKAVTNSLASI	LKAVTNSLA	SB
0701	All populations	24	IVFINFHNNGQDHLLKAVTNSLASI	LLKAVTNSL	WB
0802	Native Americans	26	IVFINFHNNGQDHLLKAVTNSLASI	LKAVTNSLA	WB
1301	All populations	24	IVFINFHNNGQDHLLKAVTNSLASI	LLKAVTNSL	WB
1501	Caucasians	26	IVFINFHNNGQDHLLKAVTNSLASI	LKAVTNSLA	WB

^aThe Smp145 epitopes that showed affinity for MHC-II proteins in humans (HLA-DRB1*0101, HLA-DRB1*0401, HLA-DRB1*0701, HLA-DRB1*0801, HLA-DRB1*1301, and HLA-DRB1*1501) in different ethnic groups of the population were identified.

^bWB, weak affinity; SB, strong affinity.