TABLE 1.

In vitro micronucleus (MN) assay results with mitomycin C (a direct acting clastogen without metabolic activation) and colchicine (an aneugen).

	% MN	% MN
	10% V/V FBS	0% V/V FBS
Untreated (0 μg/mL)	0.2 (±0.4)	0.2 (±0.4)
Mitomycin C (0.05 μg/mL)	1 (±0.8)	1.3 (±0.5)
Mitomycin C (0.15 μg/mL)	2.8 (±3.6)	1.5 (±1.0)
Colchicine (0.03 μg/mL)	11.3 (±5.8)*	7.3 (±1.7)*
Colchicine (0.09 μg/mL)	7.5 (±2.6)*	10.0 (±5.1)*
*p < 0.05 (when compared to relevant untreated control)