Table 3.
Description | Gene markers | STAD | |||
---|---|---|---|---|---|
Tumor | Normal | ||||
R | p | R | p | ||
Monocyte | CD86 | 0.170 | ** | 0.640 | *** |
CD115 (CSF1R) | 0.250 | *** | 0.420 | 0.012 | |
TAM | CCL2 | 0.120 | 0.015 | -0.051 | 0.770 |
CD68 | 0.110 | 0.031 | 0.370 | 0.028 | |
IL10 | 0.180 | ** | 0.530 | ** | |
M1 Macrophage | INOS(NOS2) | 0.023 | 0.640 | 0.250 | 0.140 |
IRF5 | 0.190 | *** | 0.071 | 0.680 | |
COX2(PTGS2) | 0.050 | 0.320 | -0.170 | 0.310 | |
M2 Macrophage | CD163 | 0.033 | 0.510 | -0.250 | 0.140 |
VSIG4 | 0.053 | 0.280 | 0.050 | 0.770 | |
MS4A4A | 0.150 | * | 0.094 | 0.590 | |
T cell exhaustion | PD-1(PDCD1) | 0.170 | ** | 0.740 | *** |
PDL1 | -0.009 | 0.850 | 0.080 | 0.640 | |
CTLA4 | 0.100 | 0.038 | 0.680 | *** | |
LAG3 | 0.120 | 0.013 | 0.650 | *** | |
TIM-3(HAVCR2) | 0.160 | * | 0.530 | ** | |
GZMB | −0.016 | 0.750 | 0.690 | *** |
STAD, stomach adenocarcinoma; TAM, tumor-associated macrophage; R, R-value of Spearman’s correlation.
*p < 0.01; **p < 0.001; ***p < 0.0001.