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. 2023 Jul 4;13:1142017. doi: 10.3389/fonc.2023.1142017

Table 3.

Correlation analysis between GHRL and related genes and markers of immune cells in Gene Expression Profiling Interaction Analysis (GEPIA).

Description Gene markers STAD
Tumor Normal
R p R p
Monocyte CD86 0.170 ** 0.640 ***
CD115 (CSF1R) 0.250 *** 0.420 0.012
TAM CCL2 0.120 0.015 -0.051 0.770
CD68 0.110 0.031 0.370 0.028
IL10 0.180 ** 0.530 **
M1 Macrophage INOS(NOS2) 0.023 0.640 0.250 0.140
IRF5 0.190 *** 0.071 0.680
COX2(PTGS2) 0.050 0.320 -0.170 0.310
M2 Macrophage CD163 0.033 0.510 -0.250 0.140
VSIG4 0.053 0.280 0.050 0.770
MS4A4A 0.150 * 0.094 0.590
T cell exhaustion PD-1(PDCD1) 0.170 ** 0.740 ***
PDL1 -0.009 0.850 0.080 0.640
CTLA4 0.100 0.038 0.680 ***
LAG3 0.120 0.013 0.650 ***
TIM-3(HAVCR2) 0.160 * 0.530 **
GZMB −0.016 0.750 0.690 ***

STAD, stomach adenocarcinoma; TAM, tumor-associated macrophage; R, R-value of Spearman’s correlation.

*p < 0.01; **p < 0.001; ***p < 0.0001.