Table 2. In vitro effect of P96 at different concentrations against juveniles, males and females of Schistosoma japonicum.
| Concentration (μmol/L) | 24h | 48h | 72h | ||||
|---|---|---|---|---|---|---|---|
| Mortality rate (%) | Viability score (Mean ± SE)/ Viability reduction rate (%) | Mortality rate (%) | Viability score (Mean ± SE)/ Viability reduction rate (%) | Mortality rate (%) | Viability score (Mean ± SE)/ Viability reduction rate (%) | ||
| Juvenile | P96[25] | 61.1 | 0.94±0.30/68.7 | 61.1 | 0.94±0.30/68.7 | 61.1 | 0.94±0.30/68.7 |
| P96[50] | 82.2 | 0.20±0.07/93.3 | 82.2 | 0.23±0.08/92.3 | 82.2 | 0.20±0.07/93.3 | |
| PZQ[100] | 25.0 | 1.20±0.19/60.0 | 35.0 | 1.00±0.19/66.7 | 40.0 | 0.80±0.17/73.3 | |
| Control | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | |
| Male | P96[25] | 85.7 | 0.14±0.08/95.3 | 66.7 | 0.33±0.11/89.0 | 71.4 | 0.33±0.13/89.0 |
| P96[50] | 90.5 | 0.10±0.07/96.7 | 90.5 | 0.14±0.10/95.3 | 90.5 | 0.10±0.07/96.7 | |
| PZQ[100] | 46.7 | 0.53±0.13/82.3 | 66.7 | 0.33±0.13/89.0 | 80.0 | 0.2±0.11/93.3 | |
| Control | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | |
| Female | P96[25] | 29.6 | 0.74±0.10/75.3 | 33.3 | 0.67±0.09/77.6 | 37.7 | 0.63±0.09/79.0 |
| P96[50] | 40.0 | 0.60±0.11/80.0 | 50.0 | 0.55±0.14/81.7 | 40.0 | 0.60±0.11/80.0 | |
| PZQ[100] | 40.0 | 0.67±0.16/77.7 | 66.7 | 0.40±0.11/86.7 | 73.3 | 0.27±0.12/91.0 | |
| Control | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | 0 | 3.00±0.00/0.0 | |