Table 2. Genetic changes in evolved bcy1Δ strains.
Gene | Nucleotide change | Amino acid change | Chromosome Duplications | |
---|---|---|---|---|
EWY55 | OPI1 | T715G | S239A | Chr. I |
TPK1 | G829C | A277P | ||
TOA1 | T354A | N118K | ||
RIM8 | C1591T | Q531* | ||
EWY87-1 | - | - | - | Chr. VIII |
EWY87-3 | RPA43 | A751G | S251N | - |
EWY89-1 | HSC82 | G235C | D79H | Chr. X, XVI |
EWY89-2 | - | Chr. I, X, XVI, XIV560217-625584 | ||
EWY89-3 | HSC82 | G235C | D79H | Chr. I, IX, X, XVI, XIV560217-625585 |