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. 2023 Jul 6;29(7):1793–1803. doi: 10.1038/s41591-023-02429-x

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — The odds ratio per standard deviation (OR/SD) with 95% confidence intervals for prevalent coronary artery disease (CAD) risk of the GPS_Mult was assessed in a logistic regression model adjusted for age, sex, genotyping array, and the first ten principal components of genetic ancestry in the European ancestry validation dataset of the UK biobank (N = 308,264 independent participants) stratified by sex and age subgroups. P values are derived from a t-test implemented in the GLM function in R and are two-sided.