Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 15;29(7):1662–1670. doi: 10.1038/s41591-023-02397-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 7 — a) For each gene, accessibility in each single nucleus is plotted (quantified via ArchR GeneScore). The n for each brain sample is the number of nuclei in the microglia cluster (C6) analyzed in a single experiment for each sample, which is listed in Supplementary Table 15. n = 7,982 nuclei for C7-monocyte and n = 2,369 nuclei for C8-DC. b) Fold change and statistical significance when comparing all pairs of groups for SALL1 (left) and ANPEP (right). (A-B) Within the microglia cluster (C6), cells are split by donor and brain region. Aggregated Corces 2020 microglia, as well as C7-Monocyte and C8-DC clusters, are included for reference. Statistical significance and fold change was computed for all pairs of groups for all GeneScores using the Wilcoxon test. * denotes FDR < 0.05.