. 2023 Mar 30;43(6):1229–1240. doi: 10.1007/s10875-023-01475-x

Table 4.

Overview of lipoproteins in CVID compared to healthy controls

Particle concentration	Phenotype	Mean value	P-value
XXL-VLDL	CVID	1.50 × 10⁻¹⁰	0.045^b
XXL-VLDL	Controls	1.10 × 10⁻¹⁰	0.045^b
XL-VLDL	CVID	7.08 × 10⁻¹⁰	0.028^b
XL-VLDL	Controls	4.61 × 10⁻¹⁰	0.028^b
L-VLDL	CVID	4.62 × 10⁻⁹	0.046^a
L-VLDL	Controls	3.11 × 10⁻⁹	0.046^a
M-VLDL	CVID	1.68 × 10⁻⁸	0.038^a
M-VLDL	Controls	1.28 × 10⁻⁸	0.038^a
S-VLDL	CVID	2.72 × 10⁻⁸	0.014^a
S-VLDL	Controls	2.18 × 10⁻⁸	0.014^a
XS-VLDL	CVID	3.52 × 10⁻⁸	0.019^a
XS-VLDL	Controls	3.09 × 10⁻⁸	0.019^a
IDL	CVID	9.50 × 10⁻⁸	0.417^a
IDL	Controls	9.10 × 10 − 8	0.417^a
L-LDL	CVID	0.285	0.534^a
L-LDL	Controls	0.279	0.534^a
M-LDL	CVID	1.24 × 10⁻⁷	0.522^a
M-LDL	Controls	1.19 × 10⁻⁷	0.522^a
S-LDL	CVID	1.45 × 10⁻⁷	0.516^a
S-LDL	Controls	1.40 × 10⁻⁷	0.516^a
Cholesterol	Phenotype	Mean value	P-value
TC	CVID	2.139	0.930^a
TC	Controls	2.128	0.930^a
VLDL-C	CVID	0.598	0.020^a
VLDL-C	Controls	0.486	0.020^a
LDL-C	CVID	1.400	0.704^a
Triglycerides	Phenotype	Mean value	P-value
Triglycerides	CVID	1.251	0.021^a
Triglycerides	Controls	0.999	0.021^a
VLDL-triglycerides	CVID	0.863	0.029^a
VLDL-triglycerides	Controls	0.651	0.029^a
LDL-triglycerides	CVID	0.156	0.047^a
LDL-triglycerides	Controls	0.137	0.047^a
HDL-triglycerides	CVID	0.127	0.494^a
HDL-triglycerides	Controls	0.122	0.494^a

Data is from the Subset cohort (40 CVID and 28 healthy controls). CVID, common variable immunodeficiency; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very-low-density lipoprotein. The significant P-values are marked in bold as well as the phenotype that was significantly increased in either CVID or controls.

^aStudent’s t-test.

^bMann–Whitney U test.