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. 2023 Apr 4;48(9):1257–1266. doi: 10.1038/s41386-023-01572-w

Fig. 2. Classical psychedelics and ketamine suppress the production of social ultrasonic vocalizations.

Fig. 2

A Schematic of the setup. B, C Example recordings of USVs. D Timeline of experiment. E Number of USVs recorded on sessions before and after 1 mg/kg psilocybin administration. Bar, mean. Line, individual animals. F Similar to (E) for 20 mg/kg 5-MeO-DMT. G Similar to (E) for 10 mg/kg ketamine. H Results in (E–G) tabulated as percent changes. Bar, mean. Circle, individual animals. I Proportions of USVs classified into the 11 types, comparing sessions before and after 1 mg/kg psilocybin administration. Black, saline. Red, psilocybin. Data pooled from all animals by treatment condition. J Similar to (I) for 20 mg/kg 5-MeO-DMT. K Similar to (I) for 10 mg/kg ketamine. L Example USV recordings for each of the 11 types, as well as an example sound classified as noise. n = 15 mice.