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. 2023 Jul 18;8:17. doi: 10.1038/s41525-023-00363-y

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Three different sources of gene sets totaling 19 are indicated by color (gene sets used by the PCGC to investigate sporadic CHD are indicated; black box). Y-axis in the left denotes the number represented by the bars (three bars per gene set): the total number of genes included in each gene set for the weighted analysis, the total number of 22q11.2DS-CTD cases and controls. Genes were weighted by gene expression level (blue dots indicate P-value; scale on Y-axis; red star is significant after FDR correction).