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. 2023 Jul 18;14:4297. doi: 10.1038/s41467-023-40086-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Cytokine antibody array was performed with cultured medium from control, dasatinib treated and HCK KO BMDMs. B Quantification of cytokines with the average of two dots pixel density from cytokine assay. qPCR (C) and western blot (D) demonstrated that HCK KO decreased M1 and increased M2 macrophage polarization in BMDM cells. BMDM were isolated from WT and HCK KO mice and induced with LPS/IFNγ or IL-4 after culture for 7 days. C, D ^*p < 0.05. Dasa: dasatinib. Source data are provided as a Source Data file.