. Author manuscript; available in PMC: 2024 Jul 1.

Published in final edited form as: Alzheimers Dement. 2023 Jan 19;19(7):2966–2974. doi: 10.1002/alz.12935

Table 3.

Association of SBP and mean SBP with risk of all-cause dementia.

	SBP per 5 mmHg (HR, 95% CI)	p-value		Mean SBP per 5 mmHg (HR, 95% CI)	p-value
Visit 0	1.02 (0.99,1.05)	0.056
Visit 2	1.01 (0.99, 1.03)	0.495	3 years	1.03 (0.99, 1.06)	0.053
Visit 5	1.01 (0.98, 1.03)	0.662	6 years	1.04 (0.99, 1.08)	0.061
Visit 8	1.01 (0.97, 1.04)	0.699	9 years	1.02 (0.96, 1.07)	0.559
Visit 11	1.04 (0.99, 1.09)	0.055	12 years	1.02 (0.95, 1.10)	0.555

Analyses were adjusted for baseline age, sex, race, education, history of vascular risk factors burden (smoking, hypertension and diabetes mellitus), vascular diseases burden (stroke, heart disease and claudication), and medication use (antihypertensive, cardiac, lipid lowering and mental health medications). Dementia cases were censored before corresponding SBP visits or during mean SBP periods. Abbreviations: SBP: systolic blood pressure; HR: hazard ratios; CI: confidence interval.