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. Author manuscript; available in PMC: 2024 Feb 16.
Published in final edited form as: Mol Psychiatry. 2023 Jan 19;28(7):2764–2810. doi: 10.1038/s41380-022-01935-7

TABLE 2:

PROPORTION OF POSITIVE STUDIES FOR SUICIDE AND SUICIDE ATTEMPT AND HIGHEST LEVEL OF EVIDENCE FOR EACH

Diagnosis Suicide
(N positive/total N)
Highest Evidence Level for Suicide Suicide Attempt
(N positive/total N)
Highest OCEBM Evidence Level for Suicide Attempt#
Intellectual Disability 0 3/3 3 *
Autism Spectrum D/O 1/1 1 6/6 3 *
Attention Deficit Hyperactivity D/O 3/3 1 * 6/7 1 *
Specific Learning D/O 0 1/1 1
Tic D/O 1/1 1 1/2 1
Psychotic D/O NOS 0 1/1 2
Schizophrenia 1/2 3 2/2 2
Schizoaffective D/O 1/1 3 1/1 2
First Episode Psychosis 0 2/2 3
Delusional D/O 0 1/2 3
Acute Transient Psychotic D/O 1/1 2 1/1 3
Bipolar D/O 8/8 2 * 8/9 3 *
Cyclothymic D/O 0 1/1 3
Disruptive Mood Dysregulation D/O 0 1/1 3
Major Depressive D/O -- -- -- --
Dysthymia 0 2/2 3
Premenstrual Dysphoric D/O 0 4/4 2 *
Anxiety D/O 1/1 3 5/5 2 *
Social Phobia 0 5/7 1 *
Simple/Specific Phobia 0 2/5 1 *
Panic D/O 0 9/11 1 *
Agoraphobia 0 2/5 1 *
Generalized Anxiety D/O 1/1 3 6/9 1 *
Obsessive-Compulsive D/O 2/2 1 4/7 1 *
Body Dysmorphic D/O 1/1 3 5/5 3 *
Post-Traumatic Stress D/O 1/3 3 * 13/13 2 *
Acute Stress D/O 1/1 2 0
Adjustment D/O 1/1 3 2/2 3
Dissociative D/O 0 1/1 3
Conversion D/O 0 1/1 3
Somatoform D/O 0 1/1 3
Eating D/O 2/2 2 7/7 1 *
Anorexia Nervosa 2/2 2 9/9 1 *
Bulimia Nervosa 2/3 2 * 13/13 1 *
Binge Eating D/O 0/1 2 7/9 1 *
Insomnia 0 1/1 1
Restless Legs Syndrome 0 1/1 3
Gender Dysphoria 0 3/3 3 *
Conduct D/O 0 4/4 2 *
Oppositional Defiant D/O 0 3/3 2 *
Intermittent Explosive D/O 0 6/6 1 *
Kleptomania 0 1/1 3
Substance Use D/O 1/1 2 3/4 1 *
Alcohol Use D/O, Abuse/ Dependence 9/10 2* 9/11 1 *
OUD And Opioid Abuse 3/3 1* 3/3 1 *
Sedative, Hypnotic, Anxiolytic Use D/O 1/1 2 0
Nicotine Use D/O And Dependence 1/1 2 3/6 1 *
Cannabis Use D/O 0/2 2 4/5 2 *
Inhalant Abuse/ Dependence 0 2/3 2 *
Stimulant Use D/O 1/1 2 0
Amphetamine Use D/O 1/1 3 0
Methamphetamine Use D/O 0 1/1 3
Cocaine Dependence 0/1 2 1/1 3
Gambling D/O 2/2 3 11/11 2 *
Dementia 2/2 3 0
Huntington’s Disease 6/6 3 * 3/3 3
Parkinson’s Disease 3/3 3 * 0
Frontotemporal Dementia 0 2/2 3
Traumatic Brain Injury 6/7 1 * 1/1 1
Personality D/O 2/2 3 2/2 2
Cluster A PDs 1/1 3 0
Cluster B PDs 1/1 3 1/1 3
Cluster C PDs 1/1 3 0/1 3
Schizoid PD 0 1/1 2
Paranoid PD 0 1/1 2
Schizotypal PD 0 2/2 2
Antisocial PD 3/3 3 2/3 2 *
Borderline PD -- -- -- --
Histrionic PD 0 0/1 2
Narcissistic PD 0 1/2 2
Obsessive Compulsive PD 0 1/2 2
Avoidant PD 0 1/1 2
Dependent PD 0 1/1 2

D/O=Disorder; PD=Personality Disorder; GRAY=no published studies with evidence level>3; GREEN = 100–75% positive studies; YELLOW = 74–50% positive studies; RED=<50% positive studies; Note Some D/O Have Only a Few Studies About SB

*

≥3 studies

There is evidence for association with SB in 72/144 disorders (69 if Personality Disorder Clusters are excluded)

#

The Oxford Center for Evidence Based Medicine’s (OCEBM; 2011) guidelines level 1 signifies data is derived from a “local and current random sample surveys (or censuses);” 2 signifies data is derived from systematic review of surveys that allow matching to local circumstances; and 3 signifies data is derived from a local non-random sample. See also http://www.cebm.net/index.aspx?o=5653