Table 4.
In vitro antimalarial activity of novel heterocyclic compounds
| S. no. | Compound ID | Schizonticidal activity (µg/ml) | Parasiticidal activity (µg/ml) |
|---|---|---|---|
| 1 | 1 | 3.22 ± 0.27 | 2.68 ± 0.02 |
| 2 | 2 | 3.13 ± 0.16 | 3.08 ± 0.14 |
| 3 | 3a | > 25 | > 25 |
| 4 | 3b | No activity | No activity |
| 5 | 3c | > 25 | > 25 |
| 6 | 3d | > 25 | > 25 |
| 7 | 4 | > 25 | > 25 |
IC50 values of heterocyclic compounds were calculated using regression analysis. Values were denoted in microgram per millilitre
SD standard deviation