Table 3.

Association between pre-existing cardiovascular disease and in-hospital mortality, clinical cardiovascular complications & myocardial injury.

Variable	MODEL 0a						MODEL 1b
	Odds Ratio (95% CI) for in-hospital mortality	p value	Odds ratio (95% CI) for clinical cardiovascular complications	p value	Odds Ratio (95% CI) for myocardial injury	p value	Adjusted Odds Ratio (95% CI) for in-hospital mortality	p value	Adjusted Odds ratio (95% CI) for clinical cardiovascular complications	p value	Adjusted Odds ratio (95% CI) for myocardial injury	p value
Pre-existing cardiovascular disease	5.10 (3.68–7.06)	<0.001	1.69 (0.94–3.04)	0.078	7.86 (5.65–10.95)	<0.001	1.76 (1.21–2.55)	0.003	1.10 (0.58–2.09)	0.766	3.27 (2.23–4.79)	<0.001
Age	1.09 (1.08–1.11)	<0.001	1.02 (1.01–1.03)	<0.001	1.07 (1.06–1.08)	<0.001	1.09 (1.07–1.10)	<0.001	1.02 (1.00–1.03)	0.030	1.06 (1.05–1.07)	<0.001
Male	1.17 (0.85–1.60)	0.337	1.27 (0.79–2.02)	0.325	1.26 (0.96–1.66)	0.090	N/A	N/A	N/A	N/A	1.38 (0.98–1.93)	0.063
Hypertension	3.22 (2.30–4.50)	<0.001	1.69 (1.07–2.69)	0.025	3.84 (2.89–5.09)	<0.001	0.99 (0.66–1.48)	0.946	1.07 (0.61–1.87)	0.821	1.19 (0.81–1.74)	0.384
Hypercholesterolemia	1.87 (1.35–2.58)	<0.001	1.71 (1.05–2.76)	0.029	2.36 (1.77–3.15)	<0.001	0.79 (0.54–1.15)	0.221	1.21 (0.70–2.08)	0.504	0.83 (0.57–1.22)	0.354
Diabetes mellitus	1.84 (1.32–2.58)	<0.001	1.47 (0.89–2.44)	0.135	2.00 (1.46–2.73)	<0.001	1.06 (0.73–1.55)	0.752	1.04 (0.60–1.81)	0.885	1.07 (0.72–1.59)	0.729
Current or recent smoker (<1 year)	0.44 (0.20–0.96)	0.033	0.60 (0.21–1.66)	0.318	0.82 (0.51–1.31)	0.409	0.75 (0.33–1.75)	0.508	N/A	N/A	N/A	N/A
Chronic kidney disease (eGFR < 60 ml/min/1.73 m2)	4.08 (2.68–6.20)	<0.001	2.30 (1.10–4.80)	0.023	7.80 (4.49–13.53)	<0.001	1.83 (1.14–2.94)	0.013	1.65 (0.76–3.58)	0.209	4.41 (2.29–8.47)	<0.001

^a Model 0: Unadjusted.

^b Model 1: Variables in Model 0 with p < 0.25.