Table 2. Subgroup analysis depending on aSAH severity.
WFNS 1-3 | WFNS 4-5 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Male (n=69) | Female (n=131) | p | Male (n=56) | Female (n=87) | p | |||||
WFNS, n (%) | ||||||||||
1 | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | n.a. | (n.a.) | n.a. | (n.a.) | n.a. |
2 | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | ||
3 | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | ||
4 | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | ||
5 | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | n.a. | (n.a.) | ||
Initial GCS median (IQR) | 15 | (14-15) | 15 | (14-15) | 0.8 | 8 | (3.3-12) | 8 | (4-12) | 0.97 |
GCS on admission median (IQR) | 15 | (14-15) | 15 | (14-15) | 0.86 | 3 | (3-8) | 3 | (3-9) | 0.19 |
Decrease in vigilance | 27 | (39.1) | 54 | (41.2) | 0.88 | 51 | (91.1) | 84 | (96.6) | 0.26 |
Loss of consciousness | 17 | (24.6) | 35 | (26.7) | 0.87 | 41 | (73.2) | 67 | (77) | 0.69 |
Headache | 61 | (88.4) | 113 | (86.3) | 0.82 | 21 | (37.5) | 44 | (50.6) | 0.72 |
Acute onset headache | 49 | (71) | 90 | (68.7) | 0.74 | 19 | (33.9) | 34 | (39.1) | 0.44 |
Not acute headache | 11 | (15.9) | 23 | (17.6) | 0.85 | 2 | (3.6) | 11 | (12.6) | 0.2 |
Persistent headache | 23 | (33.3) | 44 | (33.6) | 1 | 4 | (7.1) | 11 | (12.6) | 0.76 |
Duration of headache in days | 3 | (3.1) | 4.61 | (8.7) | 0.24 | 2.4 | (2.8) | 5.29 | (6.8) | 0.38 |
Nuchal pain | 11 | (15.9) | 30 | (22.9) | 0.28 | 7 | (12.5) | 5 | (5.7) | 0.05 |
Exercise-induced headache | 13 | (18.8) | 8 | (6.1) | <0.01 | 0 | (0) | 3 | (3.4) | 0.55 |
Sexual activity-induced headache | 3 | (4.3) | 4 | (3.1) | 0.69 | 1 | (1.8) | 0 | (0) | 0.32 |
Defecation-induced headache | 1 | (1.4) | 2 | (1.5) | 1 | 0 | (0) | 2 | (2.3) | 1 |
Meningism | 11 | (15.9) | 35 | (26.7) | 0.21 | 3 | (5.4) | 5 | (5.7) | 1 |
Nausea/vomiting | 45 | (65.2) | 81 | (61.8) | 0.65 | 20 | (35.7) | 42 | (48.3) | 0.16 |
Observed seizure | 4 | (5.8) | 13 | (9.9) | 0.43 | 15 | (26.8) | 14 | (16.1) | 0.14 |
Possible seizure | 14 | (20.3) | 22 | (16.8) | 0.57 | 25 | (44.6) | 47 | (54) | 0.31 |
Seizure (observed or suspected) | 17 | (24.6) | 34 | (26) | 0.87 | 38 | (67.9) | 59 | (67.8) | 1 |
Focal neurological deficit | 14 | (20.3) | 33 | (25.2) | 0.49 | 7 | (12.5) | 19 | (21.8) | 0.42 |
Anisocoria | 2 | (2.9) | 4 | (3.1) | 1 | 6 | (10.7) | 22 | (25.3) | <0.05 |
Pupils not reactive to light | 0 | (0) | 1 | (0.8) | 1 | 9 | (16.1) | 19 | (21.8) | 0.52 |
Diplopia | 4 | (5.8) | 7 | (5.3) | 1 | 1 | (1.8) | 0 | (0) | 0.3 |
Oculomotor disorder | 2 | (2.9) | 9 | (6.9) | 0.34 | 3 | (5.4) | 2 | (2.3) | 0.31 |
Blurred vision | 2 | (2.9) | 5 | (3.8) | 1 | 0 | (0) | 0 | (0) | 1 |
Vertigo | 10 | (14.5) | 14 | (10.7) | 0.49 | 3 | (5.4) | 3 | (3.4) | 1 |
Confusion | 25 | (36.2) | 41 | (31.3) | 0.53 | 6 | 10.7 | 15 | (17.2) | 1 |
Aphasia | 3 | (4.3) | 6 | (4.6) | 1 | 3 | (5.4) | 6 | (6.9) | 1 |
Dysarthria | 6 | (8.7) | 11 | (8.4) | 1 | 2 | (3.6) | 3 | (3.4) | 0.6 |
Hemisyndrome/motor deficit | 6 | (8.7) | 12 | (9.2) | 1 | 6 | (10.7) | 14 | (16.1) | 1 |
Dys-/hyp-/paresthesia | 4 | (5.8) | 3 | (2.3) | 0.23 | 0 | (0) | 3 | (3.4) | 0.54 |
Facial paresis | 5 | (7.2) | 9 | (6.9) | 1 | 0 | (0) | 2 | (2.3) | 0.53 |
Neglect | 1 | (1.4) | 1 | (0.8) | 1 | 0 | (0) | 0 | (0) | 1 |
Cardiac arrest | 0 | (0) | 0 | (0) | 1 | 4 | (7.1) | 8 | (9.2) | 0.77 |
Hypertensive crisis | 14 | (20.3) | 20 | (15.3) | 0.43 | 6 | (10.7) | 17 | (19.5) | 0.17 |
Ear pressure/pain | 4 | (5.8) | 1 | (0.8) | 1 | 0 | (0) | 1 | (1.1) | 1 |
Abdominal pain | 1 | (1.4) | 4 | (3.1) | 0.66 | 1 | (1.8) | 1 | (1.1) | 1 |
Retrograde amnesia | 6 | (8.7) | 8 | (6.1) | 0.56 | 0 | (0) | 3 | (3.4) | 0.54 |
Visual hallucinations | 1 | (1.4) | 5 | (3.8) | 0.34 | 0 | (0) | 0 | (0) | 1 |
Behavioral change | 3 | (4.3) | 1 | (0.8) | 0.12 | 0 | (0) | 0 | (0) | 1 |
Tinnitus | 4 | (5.8) | 1 | (0.8) | 1 | 0 | (0) | 0 | (0) | 1 |