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. 2023 Mar 13;11:1149. Originally published 2022 Oct 7. [Version 2] doi: 10.12688/f1000research.124123.2

Table 2. Subgroup analysis depending on aSAH severity.

WFNS 1-3 WFNS 4-5
Male (n=69) Female (n=131) p Male (n=56) Female (n=87) p
WFNS, n (%)
 1 n.a. (n.a.) n.a. (n.a.) n.a. n.a. (n.a.) n.a. (n.a.) n.a.
 2 n.a. (n.a.) n.a. (n.a.) n.a. (n.a.) n.a. (n.a.)
 3 n.a. (n.a.) n.a. (n.a.) n.a. (n.a.) n.a. (n.a.)
 4 n.a. (n.a.) n.a. (n.a.) n.a. (n.a.) n.a. (n.a.)
 5 n.a. (n.a.) n.a. (n.a.) n.a. (n.a.) n.a. (n.a.)
Initial GCS median (IQR) 15 (14-15) 15 (14-15) 0.8 8 (3.3-12) 8 (4-12) 0.97
GCS on admission median (IQR) 15 (14-15) 15 (14-15) 0.86 3 (3-8) 3 (3-9) 0.19
Decrease in vigilance 27 (39.1) 54 (41.2) 0.88 51 (91.1) 84 (96.6) 0.26
Loss of consciousness 17 (24.6) 35 (26.7) 0.87 41 (73.2) 67 (77) 0.69
Headache 61 (88.4) 113 (86.3) 0.82 21 (37.5) 44 (50.6) 0.72
Acute onset headache 49 (71) 90 (68.7) 0.74 19 (33.9) 34 (39.1) 0.44
Not acute headache 11 (15.9) 23 (17.6) 0.85 2 (3.6) 11 (12.6) 0.2
Persistent headache 23 (33.3) 44 (33.6) 1 4 (7.1) 11 (12.6) 0.76
Duration of headache in days 3 (3.1) 4.61 (8.7) 0.24 2.4 (2.8) 5.29 (6.8) 0.38
Nuchal pain 11 (15.9) 30 (22.9) 0.28 7 (12.5) 5 (5.7) 0.05
Exercise-induced headache 13 (18.8) 8 (6.1) <0.01 0 (0) 3 (3.4) 0.55
Sexual activity-induced headache 3 (4.3) 4 (3.1) 0.69 1 (1.8) 0 (0) 0.32
Defecation-induced headache 1 (1.4) 2 (1.5) 1 0 (0) 2 (2.3) 1
Meningism 11 (15.9) 35 (26.7) 0.21 3 (5.4) 5 (5.7) 1
Nausea/vomiting 45 (65.2) 81 (61.8) 0.65 20 (35.7) 42 (48.3) 0.16
Observed seizure 4 (5.8) 13 (9.9) 0.43 15 (26.8) 14 (16.1) 0.14
Possible seizure 14 (20.3) 22 (16.8) 0.57 25 (44.6) 47 (54) 0.31
Seizure (observed or suspected) 17 (24.6) 34 (26) 0.87 38 (67.9) 59 (67.8) 1
Focal neurological deficit 14 (20.3) 33 (25.2) 0.49 7 (12.5) 19 (21.8) 0.42
Anisocoria 2 (2.9) 4 (3.1) 1 6 (10.7) 22 (25.3) <0.05
Pupils not reactive to light 0 (0) 1 (0.8) 1 9 (16.1) 19 (21.8) 0.52
Diplopia 4 (5.8) 7 (5.3) 1 1 (1.8) 0 (0) 0.3
Oculomotor disorder 2 (2.9) 9 (6.9) 0.34 3 (5.4) 2 (2.3) 0.31
Blurred vision 2 (2.9) 5 (3.8) 1 0 (0) 0 (0) 1
Vertigo 10 (14.5) 14 (10.7) 0.49 3 (5.4) 3 (3.4) 1
Confusion 25 (36.2) 41 (31.3) 0.53 6 10.7 15 (17.2) 1
Aphasia 3 (4.3) 6 (4.6) 1 3 (5.4) 6 (6.9) 1
Dysarthria 6 (8.7) 11 (8.4) 1 2 (3.6) 3 (3.4) 0.6
Hemisyndrome/motor deficit 6 (8.7) 12 (9.2) 1 6 (10.7) 14 (16.1) 1
Dys-/hyp-/paresthesia 4 (5.8) 3 (2.3) 0.23 0 (0) 3 (3.4) 0.54
Facial paresis 5 (7.2) 9 (6.9) 1 0 (0) 2 (2.3) 0.53
Neglect 1 (1.4) 1 (0.8) 1 0 (0) 0 (0) 1
Cardiac arrest 0 (0) 0 (0) 1 4 (7.1) 8 (9.2) 0.77
Hypertensive crisis 14 (20.3) 20 (15.3) 0.43 6 (10.7) 17 (19.5) 0.17
Ear pressure/pain 4 (5.8) 1 (0.8) 1 0 (0) 1 (1.1) 1
Abdominal pain 1 (1.4) 4 (3.1) 0.66 1 (1.8) 1 (1.1) 1
Retrograde amnesia 6 (8.7) 8 (6.1) 0.56 0 (0) 3 (3.4) 0.54
Visual hallucinations 1 (1.4) 5 (3.8) 0.34 0 (0) 0 (0) 1
Behavioral change 3 (4.3) 1 (0.8) 0.12 0 (0) 0 (0) 1
Tinnitus 4 (5.8) 1 (0.8) 1 0 (0) 0 (0) 1