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. 2023 Jul 5;14:1171083. doi: 10.3389/fimmu.2023.1171083

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Copyright © 2023 Pakola, Quixabeira, Kudling, Clubb, Grönberg-Vähä-Koskela, Basnet, Jirovec, Arias, Haybout, Heiniö, Santos, Cervera-Carrascon, Havunen, Anttila and Hemminki

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Flow cytometric analysis of tumors collected on day 10. (A) Changes in intratumoral CD4+, CD8+ T cells and NK cells between the groups. (B) Changes in intratumoral PD1+ and LAG3+ CD4+, CD8+ T cells and NK cells. (C) Changes in perforin surface density of intratumoral CD4+, CD8+ T and NK cells. Difference between groups measured by an unpaired T-test with Welch’s correction. Error presented as SEM. Significance denoted as p-value < 0.05 = *, < 0.01 = **. N=5 biological replicates for all experiments.