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. 2023 Jul 5;14:1171083. doi: 10.3389/fimmu.2023.1171083

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Copyright © 2023 Pakola, Quixabeira, Kudling, Clubb, Grönberg-Vähä-Koskela, Basnet, Jirovec, Arias, Haybout, Heiniö, Santos, Cervera-Carrascon, Havunen, Anttila and Hemminki

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Re-challenge animal experiment. (A) Rechallenge animal experiment plan. (B) Pooled all tumor rejection, rejection of original Panc02 and rejection of un-encountered MC-38. (C) Individual tumor growth curves (D) Evaluation of CD4+, CD8+ splenocytes and their CD62L positivity evaluating memory formation in splenocytes after 31 days. N=7 for NPTX + GEM + vIL2 group, N=3 for NPTX + GEM. Difference in tumor rejection measured with Fisher’s exact test. Difference in immune cells between groups measured by an unpaired T-test with Welch’s correction. Error presented as SEM. Significance denoted as p-value < 0.05 = *.