Table 3.
Association of genetically predicted gut microbiota with viral hepatitis.
| Methods | IVs | OR | 95% CI | p value | Egger intercept, p value | Heterogeneity (Q, p value) | MR-PRESSO (Global test p value) |
|---|---|---|---|---|---|---|---|
| Alistipes | |||||||
| IVW | 12 | 1.720 | 1.160-2.550 | 0.0069 | -0.024, 0.686 | 4.704, 0.920 | 0.951 |
| Weighted median | 12 | 1.490 | 0.891-2.494 | 0.1288 | |||
| MR-Egger | 12 | 2.538 | 0.390-16.521 | 0.3527 | |||
| MR-PRESSO | 12 | 1.720 | 1.330-2.225 | 0.0017 | |||
| Ruminococcaceae NK4A214 group | |||||||
| IVW | 13 | 1.460 | 1.063-2.006 | 0.0195 | 0.014, 0.735 | 7.206, 0.844 | 0.869 |
| Weighted median | 13 | 1.531 | 1.004-2.335 | 0.0479 | |||
| MR-Egger | 13 | 1.224 | 0.429-3.493 | 0.7134 | |||
| MR-PRESSO | 13 | 1.460 | 1.142-1.868 | 0.0108 | |||
IV, instrumental variables; OR, Odd Ratio; IVW, inverse variance weighted; Bold represents p < 0.05.